Blar i forfatter "Eiríksdóttir, Gudny"

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    • Effect of genetically low 25-hydroxyvitamin D on mortality risk: Mendelian randomization analysis in 3 large European cohorts 

      Aspelund, Thor; Grübler, Martin R.; Smith, Albert V.; Gudmundsson, Elias F.; Keppel, Martin; Cotch, Mary Frances; Harris, Tamara B.; Jorde, Rolf; Grimnes, Guri; Joakimsen, Ragnar Martin; Schirmer, Henrik; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Njølstad, Inger; Løchen, Maja-Lisa; März, Winfried; Kleber, Marcus E.; Tomaschitz, Andreas; Grove-Laugesen, Diana; Rejnmark, Lars; Swart, Karin M.A.; Brouwer, Ingeborg A.; Lips, Paul; van Schoor, Natasja M.; Sempos, Christopher T.; Durazo-Arvizu, Ramón A.; Škrabáková, Zuzana; Dowling, Kirsten G.; Cashman, Kevin D.; Kiely, Mairead; Pilz, Stefan; Gudnason, Vilmundur; Eiríksdóttir, Gudny (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-02)
      The aim of this study was to determine if increased mortality associated with low levels of serum 25-hydroxyvitamin D (25(OH)D) reflects a causal relationship by using a Mendelian randomisation (MR) approach with genetic variants in the vitamin D synthesis pathway. Individual participant data from three European cohorts were harmonized with standardization of 25(OH)D according to the Vitamin D ...

    • Non-skeletal health effects of Vitamin D supplementation: A systematic review on findings from meta-Analyses summarizing trial data 

      Rejnmark, Lars; Bislev, Lise Sofie; Cashman, Kevin D.; Eiríksdóttir, Gudny; Gaksch, Martin; Grübler, Martin; Grimnes, Guri; Gudnason, Vilmundur; Lips, Paul; Pilz, Stefan; Van Schoor, Natasja M.; Kiely, Mairead; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-07)
      Background:<br>A large number of observational studies have reported harmful effects of low 25-hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic quantitative review on characteristics of randomized clinical trials (RCTs) included in meta-analyses (MAs) on non-skeletal effects of vitamin D supplementation.<br>Methods and findings:<br>We identified systematic reviews ...

    • Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: The REFINE-Reykjavik study with comparison with the Tromsø study 

      Thorsson, Bolli; Eiríksdóttir, Gudny; Sigurdsson, Sigurdur; Gudmundsson, Elias Freyr; Bots, Michiel L.; Aspelund, Thor; Arntzen, Kjell Arne; Mathiesen, Ellisiv B.; Gudnason, Vilmundur (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-31)
      <p><i>Objectives</i>: Population statistics for carotid plaque and cardiovascular risk factors reported in scientific journals are usually presented as averages for the population or age and sex adjusted, rather than sex and age groups. Important population differences about atherosclerosis and cardiovascular risk factors may thus be missed. We compare the distribution of cardiovascular risk factors, ...